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Image: Ala111Thr allele frequency distribution0

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Description: Global frequency distribution of Ala111Thr allele of the SLC24A5 gene. Ancestral allele is shown in yellow, derived allele in blue. This is a A/G SNP in the coding region of SLC24A5 gene. This SNP results in non-synonymous substitution Alanine(GCA) -> Threonine(ACA) at aminoacid position 111 of the gene. The derived allele (T= Thr) has been associated with light skin pigmentation and is common in Europe, Southwest Asia, and Central Asia. This SNP has shown evidence of natural selection. This SNP is commonly included in panels of ancestry informative SNPs and in phenotype informative markers. Populations typed:118.
Title: Ala111Thr allele frequency distribution0
Credit: Own work based on the Yale School of Medicine's ALlele FREquency Database
Author: FonsScientiae
Usage Terms: Creative Commons Attribution-Share Alike 3.0
License: CC BY-SA 3.0
License Link: http://creativecommons.org/licenses/by-sa/3.0
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