kids encyclopedia robot

Image: 12 Hegasy Cas9 Immun Wiki E CCBYSA

Kids Encyclopedia Facts
Original image ‎(2,082 × 1,476 pixels, file size: 97 KB, MIME type: image/png)

Description: CRISPR-Cas9 Confers Adaptive Immunity. Left Panel: After a phage has injected its DNA into the bacterial cytoplasm, a protein complex forms consisting of Cas1 and Cas2. A sample sequence, termed protospacer, is acquired from the phage DNA by the Cas1-Cas2 complex (1). This sequence is then integrated into the CRISPR genetic locus (2). The sequence is now called a spacer. Several spacers from earlier contacts with phages are stored in the CRISPR genetic locus. Right Panel: Spacer sequences are transcribed as RNA, and Cas9 protein is synthesized (1). RNA binds to Cas9 to form a surveillance and interference complex (2). The complex then scans intracellular DNA for matching sequences (3). If a matching phage sequence is found, Cas9 destroys the DNA by cleavage (4).
Title: 12 Hegasy Cas9 Immun Wiki E CCBYSA
Credit: Own work
Author: Guido4
Usage Terms: Creative Commons Attribution-Share Alike 4.0
License: CC BY-SA 4.0
License Link: https://creativecommons.org/licenses/by-sa/4.0
Attribution Required?: Yes

The following page links to this image:

kids search engine
All content from Kiddle encyclopedia articles (including the article images and facts) can be freely used under Attribution-ShareAlike license, unless stated otherwise.