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Image: PLoSBiol3.5.Fig1bNucleus46Chromosomes

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Description: Top: FISH (Fluorescence in situ hybridization) labeling of all 24 different human chromosomes (1 - ­22, X, and Y) in a fibroblast nucleus, each with a different combination of in total seven fluorochromes. Shown is a mid-plane of a deconvoluted image stack which was recorded by wide-field microscopy. Bottom: False color representation of all chromosome territories visible in this mid-section after computer classification.
Title: PLoSBiol3.5.Fig1bNucleus46Chromosomes
Credit: Bolzer et al., (2005) Three-Dimensional Maps of All Chromosomes in Human Male Fibroblast Nuclei and Prometaphase Rosettes. PLoS Biol 3(5): e157 DOI: 10.1371/journal.pbio.0030157, part of Figure 1.
Author: Andreas Bolzer, Gregor Kreth, Irina Solovei, Daniela Koehler, Kaan Saracoglu, Christine Fauth, Stefan Müller, Roland Eils, Christoph Cremer, Michael R. Speicher, Thomas Cremer
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