Image: Spike omicron mutations top

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Description: Positions of mutations in the SARS-CoV-2 Omicron variant compared to the original strain, showing amino acid substitutions (yellow), deletions (red), and insertions (green). In this trimeric structure, two monomers (gray and light blue) have their receptor-binding domains in the "down" conformation while one (dark blue) is in the "up" or "open" conformation. "Top" view is looking toward the membrane and shows the receptor-binding domains. Mutation data source from WHO. Rendered from PDB: 6VYB.

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein. Walls, A.C., Park, Y.J., Tortorici, M.A., Wall, A., McGuire, A.T., Veesler, D. (2020) Cell 181: 281

PubMed: 32155444 DOI: 10.1016/j.cell.2020.02.058
Author: Opabinia regalis
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2021

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