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Ibuprofen facts for kids

Kids Encyclopedia Facts
Systematic (IUPAC) name
(RS)-2-(4-(2-methylpropyl)phenyl)propanoic acid
Quick facts for kids
CAS number 15687-27-1
ATC code M01AE01
PubChem 3672
DrugBank APRD00372
ChemSpider 3544
Chemical data
Formula C13H18O2 
Mol. mass 206.28
SMILES eMolecules & PubChem
Physical data
Melt. point 76 °C (169 °F)
Pharmacokinetic data
Bioavailability 49–73%
Protein binding 99%
Metabolism Hepatic (CYP2C9)
Half life 1.8–2 hours
Excretion Renal
Therapeutic considerations
Licence data

US FDA:link

Pregnancy cat.


Legal status

Unscheduled(AU) GSL(UK) OTC(US)

Routes Oral, rectal, topical, and intravenous

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) widely marketed under various trademarks including Act-3, Advil, Brufen, Motrin, Nuprin, and Nurofen; a standing joke about some athletes' regular use has produced "Vitamin I" as a slang term for it. It is used for relief of symptoms of arthritis, primary dysmenorrhoea, and fever; and as an analgesic, especially where there is an inflammatory component. Ibuprofen was developed by the research arm of Boots Group.


Nurofen tablets on pharmacy shelf
Nurofen tablets on pharmacy shelf

Approved clinical indications for ibuprofen include:

  • rheumatoid arthritis (DMARDs should also be considered)
  • osteoarthritis, ibuprofen can reduce pain and, if present, joint inflammation
  • juvenile rheumatoid arthritis, alone or with corticosteroids
  • primary dysmenorrhoea (ibuprofen proved superior to placebo, aspirin, and propoxyphen)
  • fever
  • pericarditis, chiefly after mycardial infarction, to reduce pain, fever and inflammation
  • minor aches and pains such as toothache, backache, fever and pain associated with common flu, symptomatic relief of influenza, shingles, and postoperative pain
  • sport injuries and pain after mild to moderate trauma
  • headache including mild to moderate migraine attacks

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