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Image: DE cycle

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Description: An example of directed evolution with comparison to natural evolution. The inner cycle indicates the 3 stages of the directed evolution cycle with the natural process being mimicked in brackets. The outer circle demonstrates steps a typical experiment. The red symbols indicate functional variants, the pale symbols indicate variants with reduced function.
Title: DE cycle
Credit: Thomas, Shafee, (2014). "Evolvability of a viral protease: experimental evolution of catalysis, robustness and specificity". PhD Thesis. University of Cambridge.
Author: Thomas Shafee
Usage Terms: Creative Commons Attribution 4.0
License: CC BY 4.0
License Link: http://creativecommons.org/licenses/by/4.0
Attribution Required?: Yes

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