Oculocerebrorenal syndrome facts for kids

Lowe Syndrome, also known as Oculocerebrorenal syndrome, is a very rare condition that people are born with. It is a genetic disorder that mainly affects three parts of the body: the eyes, the brain, and the kidneys.

People born with Lowe Syndrome often have cloudy eye lenses, a condition called cataracts. This means their eyes are not totally clear. Many also develop problems with their kidneys when they are young. The brain can also develop differently, which might cause children to learn things more slowly. Sometimes, people with Lowe Syndrome may also have epilepsy, which causes seizures.

What Causes Lowe Syndrome?

Lowe Syndrome happens because of a small change, or defect, in a gene found on the X chromosome. Because of this, many more boys are affected by Lowe Syndrome than girls.

History of Lowe Syndrome

The syndrome is named after Dr. Charles Lowe. He was the first person to describe this condition in 1952.

How Rare is Lowe Syndrome?

Lowe Syndrome is very rare. It affects about one out of every half a million babies born alive.

Images for kids

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  Fibroblasts are cells that help make connective tissue.

See also

In Spanish: Síndrome de Lowe para niños