Burst kinetics is a form of enzyme kinetics. Upon adding enzyme to substrate, a large initial velocity is exhibited that levels off once all enzymes have been saturated. At this point enzyme velocity linearly increases. The initial high velocity is called the burst phase.
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Dihydrofolate reductase from E. coli with its two substrates dihydrofolate (right) and NADPH (left), bound in the active site. The protein is shown as a ribbon diagram, with alpha helices in red, beta sheathes in yellow and loops in blue. Generated from 7DFR.
