Columbus is an unincorporated community in Johnson County, in the U.S. state of Missouri.
The county seat was once located at Columbus. The town site was platted in 1836. A post office called Columbus was in operation from 1837 until 1920. The community was named for Christopher Columbus.
Coordinates: 38°51′31″N 93°53′27″W / 38.85861°N 93.89083°W