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Pantothenate kinase-associated neurodegeneration facts for kids

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Pantothenate kinase-associated neurodegeneration or Hallervorden Spatz disease is a rare disease primarily characterized by extrapyramidal symptoms and dementia, or extreme forgetfullness. Hallervorden-Spatz disease is degenerative brain disease, meaning the longer a person has it the worse the effects become. Scientists think it is caused by a build up of too much Iron in the brain.

Pkan-basal-ganglia-MRI
Iron deposit in globus pallidus, imaging by MRI

Symptoms

The effects of the disease usually start at a young age and often result in a quick death. Some effects include:

  • Shaking of the arms and legs
  • Weakness
  • Muscle spasms

Related pages

  • Zumrova Alena et al. 2005. First cases in the Czech Republic of the Hallervorden-Spatz Disease resulting from mutation in the Pantothenate Kinase 2 Gene Neuroendocrinology Letters No.3:26

See also

Kids robot.svg In Spanish: Neurodegeneración asociada a pantotenato quinasa para niños

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