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Dr

Ruth Mitchell McKernan

17.3216.017 Innovate2017 Dr Ruth McKernan Gareth Russell Environmental Street Furniture 1 4.2MB.jpg
Born March 1958 (age 66)
Nationality British
Alma mater King's College London
Genre Academic and Popular Science
Subject Neuroscience
Notable works Billy's Halo

Dr. Ruth Mitchell McKernan CBE (born 1958) is a British neuroscientist known for her work on ligand-gated ion channels, and for services to business and innovation for which she was appointed CBE in 2013. She is a founding director of Astronautx, a start-up researching dementia treatments targeting astrocytes.

Career

McKernan was born in March 1958. She studied biochemistry and pharmacology at undergraduate level, graduating from King's College London with first class honours. She earned her PhD researching anti-depressant drugs at the University of London in the Institute of Psychiatry. McKernan then held research positions at St Mary's Hospital medical school on a British Heart Foundation scholarship, before moving to the United States in 1985 to become a Fulbright scholar at University of California in San Diego. In 1987 she moved to Merck where she worked for 18 years, leading their Neuroscience Research Centre from 2001, before moving to Pfizer in 2005 where she held a number of senior roles including Senior Vice President and Chief Scientific Officer of the company's Neusentis unit.

Returning to the United Kingdom, McKernan was Chief Executive of government-funded Innovate UK from 2015 to 2018, where she led the development of the Industrial Strategy Challenge Fund and promoted the importance of greater diversity in innovation. She announced her intention to step down as Chief Executive in 2018, two years before the end of the five-year appointment, stating "the introduction of UK Research and Innovation is the natural transition point and an opportunity for a new leader to refine the organisation".

McKernan is a trustee of Alzheimer's Research UK and honorary fellow of the British Pharmaceutical Society.

She is a venture partner at the Dementia Discovery Fund (DDF), a specialist venture capital fund which is part of SV Health Investors, whose ultimate controlling party is Kate Bingham. In 2019 she was a founding director of Astronautx Limited, a start-up company formed by DDF to conduct research into dementia treatments by correcting disrupted brain physiology.

In November 2019 it was announced that McKernan had been elected as the Chair of the UK BioIndustry Association.

Awards and honours

In 1993, McKernan received the ABSW Science Writers' Award for her science articles in The Independent.

She was appointed CBE in the 2013 Birthday Honours for services to business and innovation.

Interests

McKernan's interests include science-writing and gardening. She also acts as a spokesperson for Women in Innovation.

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