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Anita Harding
Born (1952-09-17)17 September 1952
Died 11 September 1995(1995-09-11) (aged 42)
Nationality Irish-British
Education King Edward VI High School
Alma mater UCL Medical School
Occupation Neurologist
Known for The first identification of a mitochondrial DNA mutation in human disease, and the concept of tissue heteroplasmy of mutant mitochondrial DNA
Spouse(s)
P.K. Thomas
(m. 1977⁠–⁠1995)

Anita Elizabeth Harding (born September 17, 1952 – died September 11, 1995) was an amazing scientist. She was an Irish-British neurologist, which is a doctor who studies the brain and nervous system. She became a professor at the University of London.

Anita Harding is famous for a big discovery. She and her team found the first problem, or "mutation," in something called mitochondrial DNA. Mitochondria are like tiny power plants inside our cells. This discovery helped us understand many diseases. She also started the first research group in the UK to study how genes affect brain diseases. This happened in 1985 at the UCL Institute of Neurology.

About Anita Harding

Anita Harding was born in Ireland. She went to school at the King Edward VI High School for Girls. Later, she studied medicine at the Royal Free Hospital Medical School. She became a qualified doctor in 1975.

Two years later, she married another neurology professor, P.K. Thomas. She continued her training to become a neurologist. She worked at different hospitals and labs. She learned about a new field called neurogenetics. This field studies how our genes can cause problems with our brain and nerves.

In 1985, Anita Harding started the first research group in the UK. This group focused on neurogenetics at the UCL Institute of Neurology. She was a lecturer there and became a senior lecturer in 1986. She held this important position for nine years.

In 1988, Anita Harding helped create the European Neurological Society. This group helps neurologists across Europe work together.

Sadly, Anita Harding passed away from cancer. She was just 42 years old. She was known for her great sense of humor. She even called herself the "wobbly doctor." When she learned she was very ill, she joked, "At least I won't have to buy Windows 95!"

In 1995, after she passed away, she received a special award. It was the Association of British Neurologists Medal. This award recognized her important contributions to understanding brain diseases.

Her Important Discoveries

Anita Harding made many important discoveries. Her work helped us understand diseases that affect the nervous system.

  • Understanding Nerve Diseases: She helped classify different types of nerve problems. These included peripheral neuropathies, which affect nerves outside the brain and spinal cord. She also studied hereditary ataxias, which are conditions that make it hard to control your movements.
  • Mitochondrial DNA: Her biggest discovery was finding a problem in mitochondrial DNA. This was the first time anyone found such a problem linked to a human disease. This discovery was made in a condition called Kearns–Sayre syndrome.
  • Genetic Repeats: She also helped identify "trinucleotide repeats." These are specific patterns in our DNA that can cause diseases like Huntington's disease. Huntington's disease affects the brain and can cause uncontrolled movements and other problems.

Anita Harding also studied how these diseases affect different groups of people. She wrote over 200 articles and edited three books. She and Dr. Mary Davis also created one of the largest labs in the UK. This lab helped analyze genetic problems related to brain disorders.

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