Antisuppressor facts for kids

Antisuppressor is a mutation with the response against suppression effects of nonsense suppression or suppression chemicals.

In 1976, Rieger, Michaelis, and Green have been stated:

"antisuppressor – a mutation which countreacts suppressor effects (→ nonsense suppression). Antisuppressor mutations can occur in any of the folowing components affecting the → genetic translation system (Cox 1973):

1. A ribosomal component affecting codon-anticodon recognition or tRNA binding.
2. A termination factor altered in such a way that synthesis polypeptide release from the ribosome is enhanced thus decreasing the efficiency of suppression.
3. An enzyme affecting → suppressor tRNA (either an → aminoacyl-tRNA synthetase, a base modifying enzyme affecting the anticodon, an enzyme modifaying a base or bases involved in ribosome binding, an enzyme affecting tRNA maturation, or a factor controling total tRNA)."

See also

• Suppressor gene
• Gene expression
• Nonsense suppression