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Myelofibrosis facts for kids

Kids Encyclopedia Facts

Primary myelofibrosis is a relatively rare bone marrow / blood cancer. It is currently classified as a myeloproliferative neoplasm.

Signs and symptoms

Symptoms include:

  • Abdominal fullness related to an enlarged spleen (splenomegaly).
  • Bone pain
  • Bruising and easy bleeding due to inadequate numbers of platelets
  • Cachexia (loss of appetite, weight loss, and fatigue)
  • Enlargement of both the liver and spleen
  • Fatigue
  • Gout and high uric acid levels
  • Increased susceptibility to infection, such as pneumonia
  • Pallor and shortness of breath due to anemia
  • In rarer cases, a raised red blood cell volume
  • Cutaneous myelofibrosis is a rare skin condition characterized by dermal and subcutaneous nodules.

See also

Kids robot.svg In Spanish: Mielofibrosis con metaplasia mieloide para niños

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