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Charles Brenton Huggins
Charles Brenton Huggins nobel.jpg
Huggins in 1966
Born (1901-09-22)September 22, 1901
Died January 12, 1997(1997-01-12) (aged 95)
Citizenship Canadian, American
Alma mater Acadia University
Harvard University
Known for prostate cancer
Awards Nobel Prize for Physiology or Medicine (1966)
Cameron Prize for Therapeutics of the University of Edinburgh (1956)
Gairdner Foundation International Award (1966)
Scientific career
Fields physiology
Institutions University of Michigan, University of Chicago

Charles Brenton Huggins (September 22, 1901 – January 12, 1997) was a Canadian-American physician, physiologist and cancer researcher at the University of Chicago specializing in prostate cancer. He was awarded the 1966 Nobel Prize for Physiology or Medicine for discovering in 1941 that hormones could be used to control the spread of some cancers. This was the first discovery that showed that cancer could be controlled by chemicals.


Huggins was born in Halifax, Nova Scotia, Canada. He graduated from Acadia University with a BA degree in 1920. He went on to study medicine at Harvard Medical School and received his MD degree in 1924. He served his internship and residency in general surgery with Frederick A. Coller at the University of Michigan.

Huggins established a method to measure the effect hormone changes have on prostatic function. ..... They monitored the prostate size and therapeutic efficacy by measuring serum prostatic acid phosphatase levels and concluded that androgenic activity in the body influences prostate cancer, at least with respect to serum phosphatase. Huggins was the first to use a systemic approach to treat prostate cancer.

Huggins was elected to the United States National Academy of Sciences and the American Academy of Arts and Sciences in 1949. In 1958, Huggins received the Cameron Prize for Therapeutics of the University of Edinburgh. In 1962, he was elected to the American Philosophical Society. He was awarded the Nobel Prize in Physiology or Medicine on October 13, 1966.

Huggins died on January 12, 1997, in Chicago, Illinois, aged 95. His wife died in 1983.

See also

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