Cortisone facts for kids

Kids Encyclopedia Facts
Cortisone
Cortison.svg
Cortisone-3D-balls.png
IUPAC name (8S,9S,10R,13S,14S,17R)-17-Hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione
Identifiers
CAS number 53-06-5
PubChem 222786
KEGG D07749
MeSH Cortisone
ChEBI CHEBI:16962
ATC code H02AB10,S01BA03
SMILES O=C(CO)[C@@]3(O)CC[C@H]2[C@@H]4CC\C1=C\C(=O)CC[C@]1(C)[C@H]4C(=O)C[C@@]23C
Properties
Molecular formula C21H28O5
Molar mass 360.42 g mol-1
Melting point

220/224 °C, 274 K, 34 °F

Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)

Cortisone is a 21-carbon steroid hormone. Its chemical name is 17-hydroxy-11-dehydrocorticosterone. It is one of the main hormones released by the adrenal gland in response to stress.

In chemical structure, it is closely related to cortisol. It is used to treat a variety of ailments and can be administered in various ways. Cortisone suppresses the immune system. This reduces inflammation, pain and swelling at the site of the injury. Long-term use of cortisone has risks.

Tadeus Reichstein, E.C. Kendall and P.S. Hench were awarded the Nobel Prize in Physiology or Medicine in 1950 for their discovery of cortisone.


Cortisone Facts for Kids. Kiddle Encyclopedia.