Cortisone facts for kids

Quick facts for kids Cortisone
IUPAC name	(8S,9S,10R,13S,14S,17R)-17-Hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione
Other names	17α,21-Dihydroxypregn-4-ene-3,11,20-trione; 17α,21-Dihydroxy-11-ketoprogesterone; 17α-Hydroxy-11-dehydrocorticosterone
Identifiers
CAS number	53-06-5
PubChem	222786
KEGG	D07749
MeSH	Cortisone
ChEBI	CHEBI:16962
SMILES	O=C(CO)[C@@]3(O)CC[C@H]2[C@@H]4CC\C1=C\C(=O)CC[C@]1(C)[C@H]4C(=O)C[C@@]23C
InChI InChI=1/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-15,18,22,26H,3-8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
Properties
Molecular formula	C21H28O5
Molar mass	360.42 g mol-1
Melting point	220 to 224 °C, Expression error: Unrecognized word "to". K, Expression error: Unrecognized word "to". °F
Pharmacology
ATC code
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)

Cortisone is a 21-carbon steroid hormone. Its chemical name is 17-hydroxy-11-dehydrocorticosterone. It is one of the main hormones released by the adrenal gland in response to stress.

In chemical structure, it is closely related to cortisol. It is used to treat a variety of ailments and can be administered in various ways. Cortisone suppresses the immune system. This reduces inflammation, pain and swelling at the site of the injury. Long-term use of cortisone has risks.

Tadeus Reichstein, E.C. Kendall and P.S. Hench were awarded the Nobel Prize in Physiology or Medicine in 1950 for their discovery of cortisone.

See also

In Spanish: Cortisona para niños