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Cortisone facts for kids

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IUPAC name (8S,9S,10R,13S,14S,17R)-17-Hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione
Other names 17α,21-Dihydroxypregn-4-ene-3,11,20-trione; 17α,21-Dihydroxy-11-ketoprogesterone; 17α-Hydroxy-11-dehydrocorticosterone
CAS number 53-06-5
PubChem 222786
KEGG D07749
MeSH Cortisone
SMILES O=C(CO)[C@@]3(O)CC[C@H]2[C@@H]4CC\C1=C\C(=O)CC[C@]1(C)[C@H]4C(=O)C[C@@]23C
Molecular formula C21H28O5
Molar mass 360.42 g mol-1
Melting point

220 to 224 °C, Expression error: Unrecognized word "to". K, Expression error: Unrecognized word "to". °F

ATC code
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)

Cortisone is a 21-carbon steroid hormone. Its chemical name is 17-hydroxy-11-dehydrocorticosterone. It is one of the main hormones released by the adrenal gland in response to stress.

In chemical structure, it is closely related to cortisol. It is used to treat a variety of ailments and can be administered in various ways. Cortisone suppresses the immune system. This reduces inflammation, pain and swelling at the site of the injury. Long-term use of cortisone has risks.

Tadeus Reichstein, E.C. Kendall and P.S. Hench were awarded the Nobel Prize in Physiology or Medicine in 1950 for their discovery of cortisone.

See also

Kids robot.svg In Spanish: Cortisona para niños

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