Quetiapine facts for kids
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Quetiapine
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| Systematic (IUPAC) name | |
| 2-(2-(4-dibenzo[b,f][1,4]thiazepine- 11-yl- 1-piperazinyl)ethoxy)ethanol | |
Quick facts for kids Identifiers |
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| CAS number | 111974-69-7 |
| ATC code | N05AH04 |
| PubChem | 5002 |
| DrugBank | DB01224 |
| ChemSpider | 4827 |
| Chemical data | |
| Formula | C21H25N3O2S |
| Mol. mass | 383.5099 g/mol |
| SMILES | eMolecules & PubChem |
| Physical data | |
| Solubility in water | 3.29 mg/mL (20 °C) |
| Pharmacokinetic data | |
| Bioavailability | 100% |
| Protein binding | 83% |
| Metabolism | Hepatic via CYP3A4-catalysed sulfoxidation to its active metabolite norquetiapine (N-desalkylquetiapine) |
| Half life | 7 hours (parent compound); 9-12 hours (active metabolite, norquetiapine) |
| Excretion | Renal (73%), faeces (20%) |
| Therapeutic considerations | |
| Licence data |
US FDA:link |
| Pregnancy cat. | |
| Legal status | |
| Routes | Oral |
Quetiapine (better known as Seroquel) is an antipsychotic drug used to treat bipolar disorder and unipolar major depression, though it is used off-label for anxiety problems, Tourette syndrome and autism issues. The side effects of Quetiapine include fatigue, dry mouth and being sleepy. The medication is sometimes used for PTSD.
See also
In Spanish: Quetiapina para niños
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Quetiapine Facts for Kids. Kiddle Encyclopedia.