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J. Michael Bishop
Nci-vol-8172-300 j michael bishop.jpg
Born
John Michael Bishop

(1936-02-22)February 22, 1936
Died March 20, 2026(2026-03-20) (aged 90)
Education Gettysburg College (Bachelors)
Harvard University (MD)
Known for Oncogene Virus
Awards
  • Clark Kerr Award (2020)
Scientific career
Fields Virology
Institutions

John Michael Bishop (February 22, 1936 – March 20, 2026) was an important American scientist. He was an immunologist (a scientist who studies the body's defense system) and a microbiologist (a scientist who studies tiny living things). Dr. Bishop shared the 1989 Nobel Prize in Physiology or Medicine with Harold E. Varmus. He was a professor at the University of California, San Francisco (UCSF). He also served as the head of the university, called a chancellor, from 1998 to 2009.

Discovering the Secrets of Cancer

Early Life and Education

John Michael Bishop was born in York, Pennsylvania, on February 22, 1936. He went to Gettysburg College for his first degree. Later, he studied at Harvard University Medical School. There, he earned his medical degree (MD) in 1962.

A Career in Science and Leadership

Dr. Bishop started his science career at the National Institute of Allergy and Infectious Diseases. This is part of the National Institutes of Health. He then worked for a year in Germany at the Heinrich Pette Institute. In 1968, he joined the faculty at the University of California, San Francisco. He remained a professor there for many years.

Leading UCSF

From 1998 to 2009, Dr. Bishop was the eighth chancellor of UCSF. This means he was the main leader of the university. During his time, UCSF grew a lot. He helped develop the Mission Bay campus. He also worked to get support for the university. He created a plan to make the university a welcoming place for everyone. UCSF also adopted a new goal: advancing health worldwide™.

Unlocking Cancer's Mysteries

Dr. Bishop's most famous work was with Harold Varmus. They worked together for a long time. Their biggest discovery was finding a normal cell gene (called c-src). This gene could turn into a cancer-causing gene (v-src). This happened when a virus, called Rous Sarcoma Virus, infected cells. This virus was first found in chickens in 1910.

Their discovery was very important. It helped scientists find many other genes that can cause cancer. These genes are called proto-oncogenes. They are normal genes that can change. When they change, they can lead to human cancers. These changes can be caused by viruses, radiation, or certain chemicals.

Awards and Recognition

Dr. Bishop received many awards for his work. He is best known for his Nobel Prize. This award recognized his research on retroviral oncogenes. With Harold Varmus, he found the first human oncogene, called c-Src. Their findings helped us understand how malignant tumors (growths of unhealthy cells) form. These tumors happen when normal genes in a cell change.

He was a member of important science groups. These included the National Academy of Sciences. In 2003, he received the National Medal of Science. This is one of the highest honors for scientists in the U.S. That same year, he published a book. It was called How to win the Nobel Prize: An Unexpected Life in Science. In 2008, he became a Foreign Member of the Royal Society. In 2020, he received the Clark Kerr Award. This award recognized his great leadership in education.

Remembering Dr. Bishop

Dr. Bishop passed away from pneumonia in San Francisco. He died on March 20, 2026, at the age of 90. His important discoveries helped us understand cancer much better.

Preserving His Legacy

The University of California, San Francisco Archives keeps Dr. J. Michael Bishop's papers. These include his lab notebooks, writings, and photographs. They help us remember his contributions to science.

See also

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