Karen Vilhelmi Karapetyan (born 14 August 1964) is an Armenian politician. He became the Prime Minister of Armenia in 2016 after the resignation of Hovik Abrahamyan.
On 23 April 2018, Karapetyan became acting Prime Minister following the resignation of Serzh Sargsyan. In May 2018, Nikol Pashinyan was elected Prime Minister.
Karapetyan earned a PhD in economics in 1989.