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Sir David MacMillan

FRS FRSE
David MacMillan.jpg
MacMillan in 2021
Born
David William Cross MacMillan

(1968-03-16) 16 March 1968 (age 57)
Bellshill, Scotland, United Kingdom
Citizenship United Kingdom
United States
Education Bellshill Academy
Alma mater University of Glasgow (BSc)
University of California, Irvine (MSc, PhD)
Awards Corday-Morgan medal
Member of the National Academy of Sciences (2018)
Nobel Prize in Chemistry (2021)
Scientific career
Institutions
Thesis Stereocontrolled formation of bicyclic tetrahydrofurans and Enantioselective total synthesis of eunicellin diterpenes (1996)
Doctoral advisor Larry E. Overman
Other academic advisors Ernest W. Colvin
David A. Evans
Doctoral students Vy Dong, Tehshik Yoon, Robert R. Knowles

Sir David William Cross MacMillan is a famous Scottish chemist. He is a professor of chemistry at Princeton University. From 2010 to 2015, he was also the head of the Chemistry Department there. In 2021, he won the Nobel Prize in Chemistry with Benjamin List. They won for developing something called "asymmetric organocatalysis". This is a special way to make chemical reactions happen. Sir David used his prize money to start a foundation named after his parents.

Early Life and Education

David MacMillan was born in Bellshill, Scotland, in 1968. He grew up in a nearby town called New Stevenston. His father worked in a steel factory, and his grandfather was a miner. He went to local public schools, New Stevenston Primary and Bellshill Academy. He often says that his Scottish education helped him become successful.

He studied chemistry at the University of Glasgow in Scotland. After that, in 1990, he moved to the United States. He started his advanced studies at the University of California, Irvine. There, he worked on creating new ways to make certain chemical structures. He earned his PhD in 1996.

What is Organocatalysis?

After getting his PhD, David MacMillan worked at Harvard University. He focused on making chemical reactions that create specific types of molecules.

In 1998, he started his own research at the University of California, Berkeley. Later, in 2000, he moved to Caltech. His team worked on new ways to control chemical reactions. In 2006, he became a professor at Princeton University.

MacMillan-Catalyst first generation
The first type of MacMillan catalyst

Sir David MacMillan is known as one of the founders of organocatalysis. This is a way to speed up chemical reactions using small organic molecules. These molecules are made of carbon and other common elements. Before this, chemists often used expensive or harmful metals to speed up reactions.

In 2000, MacMillan designed special organic molecules. These molecules could help chemical reactions happen more easily. He also developed catalysts that could make "asymmetric" reactions. This means they could create more of a "left-handed" or "right-handed" version of a molecule. Many molecules can exist in two forms that are mirror images of each other, like your left and right hands. In medicine, often only one "handed" version of a molecule works correctly.

MacMillan's research group has made many breakthroughs in this area. They have used these new methods to create many complex natural products. These include important chemicals found in nature. His special catalysts, called imidazolidinone catalysts, are used in many different chemical reactions.

He also developed a method called photoredox catalysis. This uses light to help chemical reactions happen.

From 2010 to 2014, MacMillan was the first editor-in-chief of a science magazine called Chemical Science.

Awards and Special Recognitions

Sir David MacMillan has received many important awards for his work. In 2022, he was made a knight by the King of the United Kingdom. This was for his great contributions to chemistry and science.

Some of his other awards include:

See also

Kids robot.svg In Spanish: David MacMillan para niños

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