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Mutation facts for kids

Kids Encyclopedia Facts
DNA replication en
Occasional errors may occur during DNA replication.
Chromosomenmutationen
Chromosome mutations

In biology, a mutation is a change in the genetic material. This means changes to the DNA or to the chromosomes which carry the DNA. These changes are heritable (can be passed on to the next generation) unless they have lethal effects.

Mutations can happen for several reasons. It can happen because of errors when meiosis produces the gametes (eggs & sperms). Damage by radiation, or by certain chemicals may cause mutations. Mutations occur at random.

Also, by derivation, an individual carrying the mutation may be called a mutant or a mutation. So is the trait (character) most obviously affected by the mutation.

Types of mutation

D1S80Demo
Gene duplication causes different lengths at a single locus (allele). Shows variation in one gene in six individuals

DNA mutations

When DNA is copied mistakes are sometimes made – these are called mutations. There are four main types of mutations:

  • Deletion, where one or more DNA bases are left out.
  • Insertion, where one or more extra base is put in.
  • Substitution, where one or more bases are changed for another base in the sequence.
  • Duplication, where whole genes are copied.

Chromosome mutations

These terms are explained in the third diagram.

  • Deletion: a piece of chromosome is lost, together with any genes which may be on it.
  • Duplication: part of a chromosome is repeated
  • Inversion: part of a chromosome is reversed end to end
  • Insertion: a smaller chromosome is added into a longer chromosome
  • Translocation: part of a chromosome gets moved onto another chromosome

Results of mutation

Mutations may be bad for the organism, or neutral, or benefit the organism. Sometimes mutations are fatal for the organism – the protein made by the 'new' DNA does not work at all, and causing the embryo to die. On the other hand, evolution is moved forward by mutations, when the new version of the protein works better for the organism.

Mutations are the ultimate source of variation, upon which natural selection acts. What happens is that some mutations affect the organism's ability to live and reproduce. This is an important part of the theory of evolution. The amount of heritable variation carried by a population can be huge, and as a result natural populations can change and adapt to conditions in their environment.

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See also

Kids robot.svg In Spanish: Mutación para niños

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