G. Marius Clore facts for kids
Quick facts for kids
G. Marius Clore
MAE FRSC FMedSci FRS
|
|
|---|---|
 |
|
| Born |
Gideon Marius Clore
London, U.K.
|
| Citizenship | British, American |
| Education | University College London and University College Hospital Medical School, London, U.K. |
| Known for | Laying the foundations for three-dimensional protein structure determination in solution by NMR, developing innovative approaches for extending NMR to larger and more complex systems, and using NMR to uncover invisible states of proteins |
| Parent(s) |
|
| Awards | •Member of the National Academy of Sciences •Fellow of the Royal Society •Fellow of the American Academy of Arts and Sciences •Foreign Member of the Academia Europaea •Royal Society of Chemistry Centenary Prize (2011) •Biochemical Society Centenary Award (2013) •Royal Society of Chemistry Khorana Prize (2021) |
| Scientific career | |
| Fields | Molecular Biophysics, Nuclear Magnetic Resonance, Structural Biology, Chemistry |
| Institutions |
|
| Doctoral advisor | Sir Arnold Burgen FRS |
| Notable students |
|
G. Marius Clore is a famous scientist who studies tiny parts of living things. He is a biophysicist, which means he uses physics to understand biology. He is also a structural biologist, meaning he figures out the shapes of molecules like proteins.
Born in London, U.K., he is now a citizen of both the U.S. and the U.K. Dr. Clore works at the National Institutes of Health (NIH) in the U.S. He is known for his important work using a method called NMR to see the 3D shapes of proteins and other large molecules. His research helps us understand how these molecules work and interact inside our bodies.
Contents
About G. Marius Clore's Life
G. Marius Clore earned his first degree in biochemistry from University College London in 1976. He then studied medicine at UCL Medical School and became a doctor in 1979. After working in hospitals, he joined the Medical Research Council in the U.K. in 1980. He received his PhD in Physical Biochemistry in 1982.
From 1984 to 1988, he led a department at the Max Planck Institute for Biochemistry in Germany. In 1988, Dr. Clore moved to the National Institutes of Health (NIH) in the U.S. The NIH is a big research center that helps improve health. He has worked there ever since, becoming a top investigator.
Dr. Clore has received many honors for his work. He is a member of the United States National Academy of Sciences and a Fellow of the Royal Society. These are very important groups that recognize leading scientists. The Royal Society praised him for being a pioneer in using NMR to study the shapes of biological molecules. They also noted his work on finding "invisible" states of molecules, which helps us understand how they move and interact.
What G. Marius Clore Researches
Dr. Clore's research focuses on understanding the tiny building blocks of life. He uses special tools to see how they are shaped and how they move.
Seeing 3D Shapes with NMR
One of Dr. Clore's main achievements is helping to develop NMR for studying the 3D shapes of molecules in liquid. Think of NMR as a way to take detailed "pictures" of molecules. He helped create new ways to use NMR to study very large and complex molecules. His work has shown how proteins, which are vital for our bodies, recognize and interact with other molecules. He also helped create a widely used computer program called XPLOR-NIH for determining molecule structures.
Finding Hidden Molecular States
Dr. Clore's team has also developed new NMR methods to find "hidden" or "invisible" states of molecules. These are states that are rare or happen very quickly. Even though they are hard to see, these states are very important for how molecules work. For example, his research has shown how proteins find their specific targets on DNA. It has also helped us understand how proteins interact with each other. This work is important for understanding diseases and even for designing new medicines.
Impact of His Scientific Work
Dr. Clore is one of the most highly recognized scientists in his field. He has written over 550 scientific articles. His work has been cited by other scientists many times, showing its big impact. He is one of only a few scientists at the NIH to be elected to both the United States National Academy of Sciences and The Royal Society.
G. Marius Clore's Personal Life
Marius Clore went to school at the Lycee Francais Charles de Gaulle in London. He also studied at University College London and UCL Medical School. Outside of science, he holds a 3rd degree black belt in Tae Kwon Do. He also used to be a cave diver. His father was Leon Clore, a film producer known for movies like The French Lieutenant's Woman.
Awards and Honors
- 2024: Elected Fellow of the UK Academy of Medical Sciences
- 2021: Murray Goodman Memorial Prize
- 2021: Honorary Doctorate of Science (DSc) from University College London
- 2021: Royal Society of Chemistry Khorana Prize
- 2020: Elected Fellow of the Royal Society
- 2020: Biophysical Society Innovation Award
- 2015: Elected Foreign Member of the Academia Europaea
- 2014: Elected Member of the United States National Academy of Sciences
- 2012: Biochemical Society 2013 Centenary Award
- 2011: Royal Society of Chemistry Centenary Prize
- 2011: Elected Fellow of the International Society of Magnetic Resonance
- 2011: Elected NIH Distinguished Investigator
- 2010: Elected Fellow of the American Academy of Arts and Sciences
- 2010: Hillebrand Award of the Washington Chemical Society
- 2009: Elected Fellow of the Biophysical Society
- 2003: Elected Member of the Lister Institute of Preventive Medicine (U.K.)
- 2001: Original member, Institute for Scientific Information (ISI) Highly Cited Researchers Database
- 1999: Elected Fellow of the American Association for the Advancement of Science
- 1993: Dupont-Merck Young Investigator Award of the Protein Society
- 1990: Elected Fellow of the Royal Society of Chemistry (U.K.)
