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Maria Leptin
MariaLeptin2017-06-22-19-35-23.jpg
Leptin in Heidelberg, 2017
President of the European Research Council
Assumed office
1 November 2021
Preceded by Jean-Pierre Bourguignon (interim)
Director of the European Molecular Biology Organization
In office
1 January 2010 – 30 October 2021
Preceded by Hermann Bujard
Succeeded by Fiona Watt
Personal details
Born (1954-09-15) 15 September 1954 (age 70)
Hamburg, Germany
Spouse Jonathan Howard
Children 2
Alma mater Basel Institute for Immunology
Heidelberg University
University of Bonn
Scientific career
Fields Developmental biology
Immunology
Institutions European Molecular Biology Organization
European Molecular Biology Laboratory
University of Cologne
Max Planck Institute for Developmental Biology
MRC Laboratory of Molecular Biology
Doctoral advisor Fritz Melchers

Maria Leptin (born September 15, 1954) is a German scientist. She studies how living things develop (developmental biology) and how their bodies fight off sickness (immunology). She is currently the president of the European Research Council. Before that, she was the director of the European Molecular Biology Organization from 2010 to 2021.

Maria Leptin's Early Life and Studies

Maria Leptin studied mathematics and biology at the University of Bonn and Heidelberg University. She first thought about becoming a teacher. However, in 1979, she decided to pursue a PhD at the Basel Institute for Immunology. This decision came after a practical class taught by researchers there.

Her PhD Research

For her PhD, Maria Leptin worked with Fritz Melchers. She focused on how B-cells become active and change into plasma cells. These cells are important parts of the body's immune response to infections. She finished her PhD in 1983.

Maria Leptin's Scientific Career

After earning her PhD in 1984, Maria Leptin joined Michael Wilcox's team. This was at the MRC Laboratory of Molecular Biology (LMB) in Cambridge. Here, she worked as a postdoctoral fellow.

Studying Development in Fruit Flies

At LMB, Maria Leptin became very interested in developmental biology. She studied how special proteins called integrins help in the early growth of Drosophila (fruit flies). In 1988, she became a staff scientist at LMB.

Research on Cell Movement

Her time at LMB sparked her interest in how cells move and change shape. She also studied gastrulation, which is a key step in early embryonic development. She began researching gastrulation in 1989. This was during a short visit to Patrick O'Farrell's group at the University of California, San Francisco.

Leading Research Groups

After her visit, she moved to the Max Planck Institute for Developmental Biology in Tübingen, Germany. There, she led a research group focusing on gastrulation until 1994. That year, she became a professor at the University of Cologne, Institute of Genetics. She still holds this position today.

Her research group in Cologne first continued studying gastrulation. Later, they shifted to looking at how the Drosophila respiratory system develops. Eventually, Maria Leptin started using zebrafish as a model organism. She used them to study the body's first line of defense, called the innate immune response.

Visiting Professor Roles

Maria Leptin also had two more experiences as a visiting professor. The first was in 2001 at the École Normale Supérieure in Paris. The second was as a visiting scientist at the Wellcome Sanger Institute in the UK between 2004 and 2005.

Leadership at EMBO and ERC

In 2009, Maria Leptin was chosen to be the director of the European Molecular Biology Organization. She started this role in January 2010. She also set up a research group at the European Molecular Biology Laboratory in Heidelberg. This group studies what makes cells take certain shapes in Drosophila. They also use live imaging to watch the innate immune response in zebrafish.

In 2018, Maria Leptin was a visiting professor of Cell and Developmental Biology at the University of Oxford. In June 2021, she was appointed as the next president of the European Research Council. She officially started this important role on November 1, 2021.

Awards and Recognitions

Maria Leptin has received many honors for her important work in science:

  • She became a member of the European Molecular Biology Organisation in 1996.
  • In 1998, she joined Academia Europaea.
  • She became a corresponding member of the North Rhine-Westphalian Academy of Sciences, Humanities and the Arts in 2010.
  • In 2016, she became a member of the German National Academy of Sciences Leopoldina.
  • She was made an Honorary Fellow of the Academy of Medical Sciences in 2017.
  • In 2022, she became a Foreign Member of the Royal Society.
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