Antony Galione facts for kids
Quick facts for kids
Antony Galione
FRS FMedSci
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Galione in 2016
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| Born | 13 September 1963 Chelmsford, England
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| Education | Felsted School |
| Alma mater | Trinity College, Cambridge |
| Spouse(s) |
Angela Clayton
(m. 1992) |
| Awards | Novartis Prize (2001) |
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| Institutions | |
| Thesis | Oscillations in intracellular calcium in the blowfly salivary gland (1989) |
| Doctoral advisor | Michael Berridge |
Antony Giuseppe Galione (born 13 September 1963) is a British scientist. He studies pharmacology, which is the study of how medicines and chemicals affect our bodies. He is a professor at the University of Oxford.
Contents
Early Life and Education
Antony Galione was born on September 13, 1963. His hometown is Chelmsford, England. He went to Felsted School in Essex. Later, he studied at Trinity College, Cambridge.
In 1985, he earned a degree in Natural Sciences. He focused on pharmacology. In 1989, he earned his PhD. His research was about how calcium signals work. He studied this in the salivary gland of the blowfly.
Research and Discoveries
Professor Galione's main research is about something called calcium signalling. Think of calcium as tiny messengers inside our cells. These messengers help control many important body functions.
Scientists found that different chemical messengers help release calcium. These messengers link signals from outside a cell to calcium stored inside. This helps us understand how calcium controls many cell processes.
Galione found that a chemical called cyclic ADP-ribose helps control calcium release. He also discovered that another chemical, NAADP, starts and coordinates calcium signals. These signals often involve different parts of the cell talking to each other.
How Calcium Messengers Work
Professor Galione developed new ways to study these messengers. He showed that they control many important cell processes. These include:
- How the Ebola virus disease affects cells.
- How fertilisation and early development (embryology) happen.
- How heart muscles squeeze (cardiac contractility).
- How special immune cells (T cells) get activated.
- How brain cells (neurons) send signals.
He also found that lysosomes are important calcium stores. Lysosomes are like recycling centers in cells. But they also play a new role in sending calcium signals. This discovery helps us understand health and disease better.
From 2006 to 2015, Professor Galione led the Department of Pharmacology. This department is at the University of Oxford.
Awards and Honours
Professor Galione has received several important awards. In 2010, he became a Fellow of the Academy of Medical Sciences. This is a special honour for medical scientists.
In 2016, he was elected a Fellow of the Royal Society (FRS). This is a very high honour for scientists in the UK. He also won the Novartis Prize in 2001. This award came from the British Pharmacological Society.
