kids encyclopedia robot

Ernst Chain facts for kids

Kids Encyclopedia Facts
Quick facts for kids
Sir

Ernst Chain

Ernst Boris Chain 1945.jpg
Chain in 1945
Born
Ernst Boris Chain

(1906-06-19)19 June 1906
Died 12 August 1979(1979-08-12) (aged 73)
Citizenship German (until 1939)
British (from 1939)
Alma mater
Known for Discovery of penicillin
Spouse(s)
(m. 1948)
Children 3
Awards Nobel Prize in Physiology or Medicine (1945)
Fellow of the Royal Society (1948)
Paul Ehrlich and Ludwig Darmstaedter Prize (1954)
Knight Bachelor (1969)
Scientific career
Fields Biochemistry
Institutions Imperial College London
University of Cambridge
University of Oxford
Istituto Superiore di Sanità
University College Hospital

Sir Ernst Boris Chain (born June 19, 1906 – died August 12, 1979) was a British scientist. He was born in Germany. He is famous for his important work on penicillin. He even won a Nobel Prize in Physiology or Medicine for it!

Early Life and Education

Penicillin Past, Present and Future- the Development and Production of Penicillin, England, 1944 D17806
Dr Ernst Chain doing an experiment in his lab at University of Oxford in 1944.

Ernst Chain was born in Berlin, Germany. His father was a chemist and businessman. In 1930, Ernst earned his degree in chemistry from Friedrich Wilhelm University in Berlin.

Moving to England

When the Nazis came to power in Germany, Chain knew it was not safe for him. He was Jewish. So, he moved to England on April 2, 1933, with very little money. A scientist named J.B.S. Haldane helped him get a job at University College Hospital in London.

A few months later, he became a PhD student at Fitzwilliam College, Cambridge. There, he studied phospholipids. In 1935, he started working at University of Oxford as a lecturer in pathology. He researched many things, like snake venom and how tumours grow. In April 1939, he became a British citizen.

The Discovery of Penicillin

The Synthetic Production of Penicillin during the Second World War TR1458
Ernst Chain in his laboratory.

In 1939, Chain joined Howard Florey. They wanted to study natural substances that could fight bacteria. This led them to look at the work of Alexander Fleming. Fleming had found penicillin nine years earlier.

Chain and Florey worked together to find out how penicillin worked. They also learned how to get the germ-killing part of penicillin and make it stronger. Their discoveries showed how useful penicillin could be as a medicine. For this amazing research, Chain, Florey, and Fleming shared the Nobel Prize in Physiology or Medicine in 1945.

Chain also helped figure out the chemical structure of penicillin in 1942. This was later confirmed by Dorothy Hodgkin using special X-ray tests.

Later Career and Life

After World War II, Chain learned that his mother and sister had died because of the Nazis. He then moved to Rome, Italy, to work at the Istituto Superiore di Sanità.

In 1964, he came back to Britain. He started and led the biochemistry department at Imperial College London. He worked there until he retired. He focused on ways to use fermentation in industry.

In 1948, Chain became a Fellow of the Royal Society. This is a very important honor for scientists.

In 1948, he married Anne Beloff. She was also a talented biochemist. As he got older, his Jewish heritage became more important to him. He was very involved with the Weizmann Institute of Science in Israel. He made sure his children learned about their Jewish faith. In 1965, he gave a famous speech called 'Why I am a Jew'.

Ernst Chain was made a Knight Bachelor in 1969. This means he was given the title "Sir."

Chain passed away in 1979 in Castlebar, Ireland. The biochemistry building at Imperial College London is named after him. A road in Castlebar is also named in his honor.

See also

  • List of Jewish Nobel laureates
kids search engine
Ernst Chain Facts for Kids. Kiddle Encyclopedia.