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Oliver Smithies
Oliver Smithies HD2009 AIC Gold Medal portrait (cropped).JPG
Born (1925-06-23)June 23, 1925
Died January 10, 2017(2017-01-10) (aged 91)
Nationality British, American
Alma mater Balliol College, University of Oxford
Known for Gel electrophoresis, gene targeting
Awards Nobel Prize in Physiology or Medicine (2007)
Scientific career
Fields Biochemistry, genetics
Institutions University of Toronto
University of Wisconsin–Madison
University of North Carolina at Chapel Hill

Oliver Smithies (23 June 1925 – 10 January 2017) was a British-American geneticist and Nobel laureate,

He invented gel electrophoresis in 1955, which is now one of the basic techniques of biochemistry and molecular biology.

Much later, he worked on the technique of homologous recombination of transgenic DNA with genomic DNA. This is the most reliable method of altering animal genomes at present, and the technique behind gene targeting and knockout mice.

Martin Evans and Mario Capecchi were also working on this idea, and they were jointly awarded the Nobel Prize in Physiology or Medicine for 2007.

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